Papers on FRAIL

Who was studied1,222 patients after transcatheter aortic valve implantation, 1 year, against controls

What changedDeath or worsening heart failure was lower with dapagliflozin in frail patients versus controls (hazard ratio 0.53)

The catchFrailty subgroups were analyzed after the fact, so the apparent treatment difference needs confirmation

Who was studied681 Danish patients with symptomatic multiple myeloma, 2 years

What changedOverall quality of life improved in frail patients with newly diagnosed myeloma but stayed unchanged with returning or treatment-resistant disease

The catchQuality-of-life changes relied on self-reports, leaving them vulnerable to reporting bias

Who was studied264 non-frail and pre-frail older adults, twelve months

What changedFalls did not clearly differ between In Balans and general physical activity advice

The catchAttendance averaged approximately two thirds of sessions, limiting conclusions about completing the intended program

Who was studied2,073 initially non-frail community-dwelling Chinese older adults, seven years

What changedPersistently lonely adults had 3.989 times the adjusted odds of developing frailty compared with consistently low loneliness

The catchLoneliness was measured with a single question

Who was studied3,316 initially non-frail older Chinese adults, 7 years

What changedGreater social isolation was linked to higher frailty risk through depression followed by declining thinking abilities

The catchDepression or cognitive decline could lead to isolation rather than follow it