What does the research say about circular RNAs?

Circular RNAs

There are 7 papers on circular RNAs in aging research: 1 trial in people, 2 in animals, 3 reviews. The newest story, Nov 9, 2026: “Gut microbe-derived compound promotes kidney aging in mice”.

Biomarker

7 papers study it140 more mention it2 findings

7 new papers in 30 daysSee all 147 papers on circular RNAs

Human trial1
Animals2
In silico1

Associations

Neurodegenerative disease

mixedin reviews1

1 study

Circular RNAs is associated with neurodegenerative disease.
“circRNAs are implicated in the biology of brain aging and the pathology of age-related neurodegenerative diseases”
Review
Circular RNAs: emerging players in brain aging and neurodegenerative diseases
The Journal of pathologyOct 21, 2022

Latest

36 papers in 12 months

Cellular and Molecular NeurobiologyNov 7

Exercise-Responsive Non-coding RNAs in Neurodegeneration and Aging: Molecular Mechanisms, Systemic Adaptations, and Biomarker Potential

ReviewExercise

Paper

BiomoleculesOct 27

Non-Coding RNAs in Prediabetes Beyond Glycemic Classification: Tissue Regulatory Networks, Progression Risk, and Intervention-Associated Dynamics

ReviewPrediabetes

Paper

Food Research InternationalMay 12

Chronic consumption of (poly)phenol-rich foods exerts multigenomic modification of genes linked to cardiometabolic health in postmenopausal women

Non-randomized trial in peopleCardiometabolic disorder

Paper

Renal FailureNov 9

Gut microbe-derived compound promotes kidney aging in mice

Reducing a circular RNA weakened the compound’s effects in male mice given it in drinking water for 16 weeks.Reducing a circular RNA weakened the compound’s effects in male mice given it in drinking water for 16 weeks.

Mouse studyKidney