Papers on circular RNAs

147 papers7 new in 30 days

Monday, November 9

Renal FailureNov 9

Gut microbe-derived compound promotes kidney aging in mice

Reducing a circular RNA weakened the compound’s effects in male mice given it in drinking water for 16 weeks.Reducing a circular RNA weakened the compound’s effects in male mice given it in drinking water for 16 weeks.

Kidney tubules show enlarged cells with dense inflammation beside smaller, orderly cells with sparse inflammation, surrounded by rings and a mouse.

Mouse studyKidney

Paper

Saturday, November 7

Cellular and Molecular NeurobiologyNov 7

Exercise-Responsive Non-coding RNAs in Neurodegeneration and Aging: Molecular Mechanisms, Systemic Adaptations, and Biomarker Potential

Figure from Cellular and Molecular Neurobiology

ReviewExercise

Paper

Friday, November 6

Research SquareNov 6

Attenuating cardiac fibrosis and apoptosis by exercise is associated with modulation of the circSlc8a1/miR-133a axis in D-galactose-treated rats

Expression levels of circular Slc81a1 and miR-133a in cardiac tissue of study groups.

Preprint: experiments in 42 ratsCardiac fibrosis

Paper

Friday, October 30

Frontiers in MedicineOct 30

RNA therapeutics for muscle wasting: bridging target validation and muscle-directed delivery

Accepted, not yet published: reviewMuscle wasting

Paper

Tuesday, October 27

BiomoleculesOct 27

Non-Coding RNAs in Prediabetes Beyond Glycemic Classification: Tissue Regulatory Networks, Progression Risk, and Intervention-Associated Dynamics

Prediabetes as a modifiable metabolic transition: established glycemic classification and potential complementary roles of non-coding RNAs.

ReviewPrediabetes

Paper

Friday, October 23

Poultry ScienceOct 23

circMARK3 serves as a sponge of miR-205a to promote senescence of follicular granulosa cells in laying hens via regulating LIN9

Identification and Validation of circMARK3.

Experiments in cellsCellular senescence

Paper

Friday, October 16

International Journal of Molecular SciencesOct 16

Circular RNAs in Skeletal Muscle Aging and Sarcopenia: Mechanistic Evidence, Biomarker Potential, and Therapeutic Readiness

Biological architecture of skeletal muscle aging and the position of current circRNA evidence.

ReviewMuscle

Paper

Friday, September 18

Preprints.orgSep 18

Circular RNAs in Skeletal Muscle Aging and Sarcopenia: Mechanistic Evidence, Biomarker Potential, and Therapeutic Readiness

Preprint: reviewMuscle

Paper

Tuesday, September 1

Frontiers in EndocrinologySep 1

CircRNAs as biomarkers for osteoporosis: a systematic review and meta-analysis

PRISMA flow diagram illustrating the literature search, screening, and study selection process.

Meta-analysis of observational studiesOsteoporosis

Paper

Friday, August 14

Gynecological EndocrinologyAug 14

Clinical value of hsa_circ_0003254 in postmenopausal osteoporosis and its role in the progression of osteoporosis

Case-control study of 207 peoplePostmenopausal osteoporosis

Paper

Wednesday, August 5

Research SquareAug 5

CircRNA-Mediated Reprogramming of Adipose-Derived Stem Cells to iPSCs for Efficient Derivation of Functional Mesenchymal Stem Cells

Preprint: experiments in human cellsInterventions

Paper

Monday, August 3

Research SquareAug 3

Downregulation of circRNA_29625 in the Hippocampus Drives Perioperative Neurocognitive Disorder by Reducing SIRT1 and Exacerbating Anesthesia/Surgery-Induced Neuroinflammation

Preprint: experiments in miceSirtuin signaling

Paper

Thursday, July 30

Frontiers in NeuroscienceJul 30

Biomarker value of plasma endothelial microvesicle-derived circRNA 0006222 in vascular ageing and carotid atherosclerosis

Case-control study of 216 peopleCarotid atherosclerosis

Paper

Wednesday, July 22

Frontiers in Molecular NeuroscienceJul 22

CircHomer1 may contribute to postoperative cognitive impairment by modulating Homer1b/mGluR5-associated signaling in the vCA1 region of aged mice

Experiments in miceSynaptic transmission

Paper

Thursday, July 16

Aging CellJul 16

Circular RNAs-Stress Granule Interplay Drives Aging-Related Proteostasis Loss

ReviewProteostasis

Paper

Tuesday, July 14

Frontiers in Cell and Developmental BiologyJul 14

Dual modes of action: direct regulation and ceRNA-mediated mechanisms of ncRNAs in dermal fibroblast senescence

ReviewCellular senescence

Paper

Friday, July 3

bioRxivJul 3

Temporal and Regional Circular RNA profiling in a Tauopathy Mouse Model: Implications for Tau Pathology and Neurodegeneration

Preprint: experiments in miceAI & data

Paper

Thursday, July 2

Nature MedicineJul 2

Blood-based circular RNAs for early diagnosis of Alzheimer's disease

Cohort study of 1,221 peopleAlzheimer's disease

Paper

Friday, June 26

GenesJun 26

Non-Coding RNAs as Emerging Biomarkers in HPV-Associated Cervical Precancer and Cancer: Molecular Mechanisms and Clinical Perspectives

Systematic reviewBiomarkers

Paper

Wednesday, June 10

bioRxivJun 10

M 6 A-modified circEZH2 Protects Endothelial Cells from Senescence and Suppresses Atherosclerosis by Stabilizing ZNF326

Preprint: experiments in miceCellular senescence

Paper

Friday, May 22

Molecular Medicine ReportsMay 22

Epigenetic research methods and animal models for intervertebral disc degeneration (Review)

ReviewMechanisms

Paper

Tuesday, May 12

Food Research InternationalMay 12

Chronic consumption of (poly)phenol-rich foods exerts multigenomic modification of genes linked to cardiometabolic health in postmenopausal women

Non-randomized trial in peopleCardiometabolic disorder

Paper

Saturday, April 11

Ecotoxicology and Environmental SafetyApr 11

Circular RNA signatures associated with nanoplastics-induced healthspan alterations in C. elegans

Experiments in wormsMechanisms

Paper

Friday, April 10

Scientific ReportsApr 10

Synthetically designed circRNA can be used to target cardiovascular relevant microRNAs to improve cellular function

Experiments in human cellsInterventions

Paper

Friday, March 27

Molecular BiomedicineMar 27

YTH N6-methyladenosine RNA binding protein 2 mediated m⁶A modification of circHIPK2 promotes cellular senescence and osteoarthritis progression by inhibiting autophagy

Experiments in miceOsteoarthritis

Paper

Wiley Interdisciplinary Reviews RNAMar 27

Therapeutic Prospects of Artificially Synthesized Circular RNA

ReviewInterventions

Paper

Thursday, March 26

Frontiers in GeneticsMar 26

Exercise stress and tissue remodeling: advances in exosome-mediated RNA-RBP networks in musculoskeletal injury repair and functional recovery

ReviewExercise

Paper

Tuesday, March 10

Ageing Research ReviewsMar 10

Decoding skin aging: Emerging roles of miRNAs, lncRNAs, and circRNAs in mechanisms, therapies, and future horizons

ReviewSkin

Paper

Thursday, March 5

CytotherapyMar 5

Lipid nanoparticle-points to consider in assessing materials quality for ribonucleic acid-based therapeutics

ReviewLipid nanoparticles

Paper

Friday, February 27

PLOS OneFeb 27

Comprehensive profiling of circRNAs reveals stimulus-specific networks and core regulators of cellular senescence

Experiments in human cellsCell cycle regulation

Paper