Cholesterol efflux
5 papers study it47 more mention it4 findings
- Humans2
- Animals1
- Cells1
Interventions
1Urolithin A
upin mouse cells1
1 study
Urolithin A
upin mouse cells1
Urolithin A increases cholesterol efflux in mouse cells.
“UA reduced ox-LDL induced cholesterol accumulation in macrophage cells and promoted cholesterol efflux from cells.”
Cellsin ox-LDL-treated RAW264.7 cells
Food & function
Upstream
2Type 2 diabetes
downin humans1
1 study
Type 2 diabetes
downin humans1
Type 2 diabetes decreases cholesterol efflux in humans (25.08±1.90 and 29.72±1.75 vs 32.86±2.07).
“HDL functionality was significantly reduced in T2DM+A (25.08±1.90) and T2DM (29.72±1.75) compared to NGT (32.86±2.07).”
Humansin T2DM and T2DM with atherosclerosis
ADA Scientific Sessions 2026 abstract
MIR33
downin mouse cells1
1 study
MIR33
downin mouse cells1
MIR33 decreases cholesterol efflux in mouse cells.
“pre-miR-33a attenuated cholesterol efflux induced by UA.”
Cellsin ox-LDL-treated RAW264.7 cells
Food & function
Associations
1ABCA1
upin humans1
1 study
ABCA1
upin humans1
ABCA1 is associated with cholesterol efflux in humans.
“HDL functionality as measured by CE was significantly reduced in patients with T2DM+A and T2DM, and positively associated with ABC transporters.”
Humansin T2DM and NGT subjects
ADA Scientific Sessions 2026 abstract
Funding
3 grants since 2020National Heart, Lung, and Blood InstituteUS$570.5kJapan Society for the Promotion of ScienceJP¥8.5m
Cardiac Calcification and Cholesterol Efflux in Older Adults
National Heart, Lung, and Blood InstituteAlbert Einstein College of MedicineUS$190.2k2020–2025
Japan Society for the Promotion of ScienceJuntendo UniversityJP¥4.2m2021–2025
Japan Society for the Promotion of ScienceHirosaki UniversityJP¥4.3m2020–2023