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A dual-targeting mRNA lipid nanoparticle restores ABCA1-dependent cholesterol homeostasis to promote repair of age-related bone defects

Bioactive Materials

  • Rab7-apt2 mRNA lnp
  • ABCA1
  • LYPLA2
  • Bone defect
  • Lysosomal cholesterol
  • Rats

The paper

Cheng M, Xi K, Ni Z et al.

Bioactive Materials · 20 Aug 2026

doi.org/10.1016/j.bioactmat.2026.08.017PubMed 42667070

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