Cardiac oxidative stress
1 paper studies it14 more mention it1 finding
- Animals1
Interventions
1Secreted klotho
downin mice1
1 study
Secreted klotho
downin mice1
Secreted klotho decreases cardiac oxidative stress in mice.
“Secreted Klotho treatment inhibited excessive cardiac oxidative stress, senescence and apoptosis in old mice and KL (-/-) mice.”
Animalsold mice and Klotho-deficient miceexogenous secreted Klothoheart
Klotho Deficiency Causes Heart Aging via Impairing the Nrf2-GR Pathway
Circulation research
Latest
4 papers in 12 monthsInternational Journal of Cardiology Cardiovascular Risk and Prevention
Cardiac, oxidative stress, and fibrosis-related biomarkers and new-onset heart failure: Systematic review and meta-analysis
Meta-analysis of observational studiesHeart failure
Life Sciences
Trimethylamine N-oxide drives cardiac aging by activating NLRP3-mediated pyroptosis
Experiments in micePyroptosis
Biomedicine & Pharmacotherapy
Oral apigenin prevents obesity-related muscular atrophy, but not obesity itself, in middle-aged rats fed a high-calorie diet
Experiments in 47 ratsInterventions
International Journal of Environmental Research and Public Health
Regular Exercise Rescues Heart Function Defects and Shortens the Lifespan of Drosophila Caused by dMnM Downregulation
Experiments in fliesExercise
Metabolites
KLF15 Regulates Oxidative Stress Response in Cardiomyocytes through NAD
Experiments in animalsMechanisms
Journal of the American Heart Association
Effects of Aging on Cardiac Oxidative Stress and Transcriptional Changes in Pathways of Reactive Oxygen Species Generation and Clearance
Experiments in animalsMechanisms
Circulation Research
Klotho Deficiency Causes Heart Aging via Impairing the Nrf2-GR Pathway
Experiments in miceInterventions