Cardiac remodeling
Disease1 paper
- Animals1
Trial sponsors
McGill University Health Centre/Research Institute of the McGill University Health Centre
1 trialPhase 4100 people
Funding
National Heart, Lung, and Blood InstituteUS$885.9k2 grants since 2024
Latest
41Persistent IFN-γ links to worse cardiac remodeling in aged mice
In 2- and 18-month-old mice of both sexes, elevated interferon-gamma showed little acute impact after myocardial infarction but tracked with…In 2- and 18-month-old mice of both sexes, elevated interferon-gamma showed little acute impact after myocardial infarction but tracked with aggravated chronic cardiac remodeling.
Killifish exhibit distinct structural changes and fibrosis during cardiac aging
Long-lived African turquoise killifish show ventricular enlargement, fibrosis, and reduced myocardial density with age rather than typical…Long-lived African turquoise killifish show ventricular enlargement, fibrosis, and reduced myocardial density with age rather than typical cardiomyocyte hypertrophy.