YODA1-FUNCTIONALIZED manganese dioxide-ferritin nanozyme

1. YODA1-FUNCTIONALIZED manganese dioxide-ferritin nanozyme inhibits cGAS–STING signalling in cells.

   “This leads to inhibition of cGAS‒STING pathway activation”

   Cellsbone mesenchymal stem cells

   Yoda1-Functionalized Nanozymes Coordinate Piezo1 Activation and Mitochondrial Protection to Reprogram the Diabetic Osteoimmune Micromilieu and Promote Vascularized Bone Repair

   Advanced science (Weinheim, Baden-Wurttemberg, Germany)·14 Oct 2026

More on cGAS–STING signalling

1. YODA1-FUNCTIONALIZED manganese dioxide-ferritin nanozyme prevents mitochondrial DNA leakage into the cytosol in cells.

   “prevents mitochondrial DNA leakage into the cytosol.”

   Cellsbone mesenchymal stem cells

   Yoda1-Functionalized Nanozymes Coordinate Piezo1 Activation and Mitochondrial Protection to Reprogram the Diabetic Osteoimmune Micromilieu and Promote Vascularized Bone Repair

   Advanced science (Weinheim, Baden-Wurttemberg, Germany)·14 Oct 2026

1. YODA1-FUNCTIONALIZED manganese dioxide-ferritin nanozyme decreases mitochondrial reactive oxygen species in cells.

   “the MF@Y nanozyme orchestrates mitochondrial homeostasis in bone mesenchymal stem cells (BMSCs), effectively scavenges mtROS”

   Cellsbone mesenchymal stem cells

   Yoda1-Functionalized Nanozymes Coordinate Piezo1 Activation and Mitochondrial Protection to Reprogram the Diabetic Osteoimmune Micromilieu and Promote Vascularized Bone Repair

   Advanced science (Weinheim, Baden-Wurttemberg, Germany)·14 Oct 2026

More on Mitochondrial reactive oxygen species