Vitamin e

Intervention5 papers2 findingsPubChem 69540411

Humans3

Associations

Colorectal cancer

downin humans1HR 0.81Low certainty

1 study

Vitamin e lowers the risk of colorectal cancer in humans (HR = 0.81, 95% CI: 0.68-0.97).
Humans
Vitamin intake and colorectal cancer incidence and mortality: evidence from a large prospective cohort · Frontiers in nutrition · 9 Sep 2026

Colorectal cancer →

Cognitive function

downin humans1Very low certainty

1 study

Vitamin e is associated with cognitive function in humans.
Humansin multivariate modelsn = 5,591
Association Between Nutritional Components and Memory Function Among Korean Adults: Analysis of the 2023 Korea National Health and Nutrition Examination Survey Data · Preprints.org · 7 Sep 2026 · Preprint

Trials

112

In trials

Type 2 diabetes
Phase 4 · Results posted · 8 trials
Non-alcoholic Fatty Liver Disease
Phase 4 · Results posted · 7 trials
Fatty Liver
Phase 4 · Results posted · 5 trials
Neoplasms
Phase 4 · Completed · 3 trials
Type 1 diabetes
Phase 4 · Completed · 3 trials
Chronic Renal Insufficiency
Phase 4 · Terminated · 2 trials

40 of 57

Pain
Phase 4 · Completed · 2 trials
Chronic hepatitis B
Phase 4 · Status unknown · 1 trial
Epilepsy
Phase 4 · Completed · 1 trial
Male infertility
Phase 4 · Active, not recruiting · 1 trial
Prostatic Neoplasms
Phase 3 · Results posted · 8 trials
Cardiovascular disease
Phase 3 · Results posted · 7 trials
Diabetes mellitus
Phase 3 · Completed · 5 trials
Heart Diseases
Phase 3 · Results posted · 5 trials
Alzheimer's disease
Phase 3 · Results posted · 4 trials
Fibrosis
Phase 3 · Completed · 4 trials
Chronic Kidney Failure
Phase 3 · Completed · 3 trials
Chronic obstructive pulmonary disease
Phase 3 · Completed · 3 trials
Colorectal Neoplasms
Phase 3 · Results posted · 3 trials
Coronary Disease
Phase 3 · Results posted · 3 trials
Myocardial Ischemia
Phase 3 · Results posted · 3 trials
Obesity
Phase 3 · Completed · 3 trials
Vascular Diseases
Phase 3 · Results posted · 3 trials
Cataract
Phase 3 · Results posted · 2 trials
Cerebrovascular Disorders
Phase 3 · Results posted · 2 trials
Colonic Neoplasms
Phase 3 · Results posted · 2 trials
Coronary Artery Disease
Phase 3 · Completed · 2 trials
Depression
Phase 3 · Completed · 2 trials
Head and Neck Neoplasms
Phase 3 · Completed · 2 trials
Lung Neoplasms
Phase 3 · Completed · 2 trials
Macular Degeneration
Phase 3 · Results posted · 2 trials
Myocardial infarction
Phase 3 · Results posted · 2 trials
Precancerous Conditions
Phase 3 · Results posted · 2 trials
Rectal Neoplasms
Phase 3 · Results posted · 2 trials
Restless Legs Syndrome
Phase 3 · Status unknown · 2 trials
Small Cell Lung Carcinoma
Phase 3 · Completed · 2 trials
Urinary Bladder Neoplasms
Phase 3 · Status unknown · 2 trials
Amyotrophic lateral sclerosis
Phase 3 · Completed · 1 trial
Delirium
Phase 3 · Completed · 1 trial
Liver cirrhosis
Phase 3 · Completed · 1 trial

Stopped

NCT00809458 · Terminated · Prostatic Neoplasms
Low rate of accrual.
NCT00740714 · Terminated · Parkinson's disease
The investigational drug is unlikely to demonstrate efficacy over placebo for this indication. However, no safety issues were discovered.
NCT00152841 · Terminated · Crohn's disease
Lack of patients
NCT03228238 · Terminated
The study was terminated early due to slow recruitment and the Principal Investigator's retirement.