Salvianolic acid a
Intervention1 paper2 findingsPubChem 5281793ChEBI 9017
- Animals1
Outcomes
2Atherosclerosis
downin mice1
1 study
Atherosclerosis
downin mice1
Salvianolic acid a protects against atherosclerosis in mice.
“decreased the size of plaque, and increased the stability of the fibrous cap.”
Animalsin ApoE -/- mice fed a high-fat diet
Salvianolic acid A eases atherosclerosis in mice by eliminating senescent vascular cells · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 27 Sep 2026
Cellular senescence
downin mice1
1 study
Cellular senescence
downin mice1
Salvianolic acid a decreases cellular senescence in mice.
“In ApoE -/- mice, SAA reduced the burden of senescent VSMCs, decreased the size of plaque, and increased the stability of the fibrous cap.”
Animalsin ApoE -/- mice fed a high-fat dietvascular smooth muscle cell
Salvianolic acid A eases atherosclerosis in mice by eliminating senescent vascular cells · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 27 Sep 2026
Latest
1Salvianolic acid A eases atherosclerosis in mice by eliminating senescent vascular cells
The compound disrupts an HSP90α complex to trigger endoplasmic reticulum stress and selectively induce apoptosis in senescent smooth muscle cells.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) · Guan X et al.