Salvianolic acid b

  • 2 independent labs in 1 country
  • Funders: National Natural Science Foundation of China and 1 more
  • Animals1
  • Cells1

Outcomes

4

Cellular senescence

downin human cells2

2 studies
  1. Salvianolic acid b decreases cellular senescence in human cells.

    “SAB effectively alleviates the cellular senescence phenotype.”

    Cellsin aging fibroblasts (BJ)

    Salvianolic acid B attenuates cellular senescence and age-related decline in muscle function via dual mTOR/TP53INP2-autophagy regulation

    Frontiers in chemistry5 Mar 2026

  2. Salvianolic acid b inhibits cellular senescence in human cells.

    “effectively suppressed HCMV-induced cellular senescence”

    Cellsin HCMV-infected WI-38 cells

    Inhibitory effect of three components derived from Salvia miltiorrhiza against human cytomegalovirus

    Virology journal2 Mar 2026

More on Cellular senescence

Autophagy

upin mice1

1 study
  1. Salvianolic acid b activates autophagy in mice.

    “potentially through promoting TP53INP2 expression to enhance autophagy”

    Animalsradiation-induced premature agingmuscle

    Salvianolic acid B attenuates cellular senescence and age-related decline in muscle function via dual mTOR/TP53INP2-autophagy regulation

    Frontiers in chemistry5 Mar 2026

More on Autophagy

Muscle function

upin mice1

1 study
  1. Salvianolic acid b improves muscle function in mice.

    “SAB ameliorates age-related decline in muscle function”

    Animalsradiation-induced premature agingmuscle

    Salvianolic acid B attenuates cellular senescence and age-related decline in muscle function via dual mTOR/TP53INP2-autophagy regulation

    Frontiers in chemistry5 Mar 2026

Senescence-associated secretory phenotype (SASP)

downin human cells1

1 study
  1. Salvianolic acid b inhibits senescence-associated secretory phenotype (SASP) in human cells.

    “SAB reduces SASP expression through modulation of the mTOR pathway.”

    Cellsin aging fibroblasts (BJ)

    Salvianolic acid B attenuates cellular senescence and age-related decline in muscle function via dual mTOR/TP53INP2-autophagy regulation

    Frontiers in chemistry5 Mar 2026

More on Senescence-associated secretory phenotype (SASP)

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