Lysosome-modulating drugs

Intervention

1 paper3 findings

Outcomes

3

Inflammation

downin reviews1

1 study
  1. Lysosome-modulating drugs decrease inflammation.

    “have demonstrated promise in restoring lysosomal function, enhancing autophagic flux, and reducing inflammatory and oxidative injury in both experimental models and early clinical settings.”

    Reviewin experimental models and early clinical settings

    Lysosomal Stress in Cardiovascular Diseases: Therapeutic Potential of Cardiovascular Drugs and Future Directions

    Biomedicines27 Apr 2025

More on Inflammation

Autophagy

upin reviews1

1 study
  1. Lysosome-modulating drugs increase autophagy.

    “have demonstrated promise in restoring lysosomal function, enhancing autophagic flux, and reducing inflammatory and oxidative injury in both experimental models and early clinical settings.”

    Reviewin experimental models and early clinical settings

    Lysosomal Stress in Cardiovascular Diseases: Therapeutic Potential of Cardiovascular Drugs and Future Directions

    Biomedicines27 Apr 2025

More on Autophagy

lysosomal function

upin reviews1

1 study
  1. Lysosome-modulating drugs improve lysosomal function.

    “several pharmacological agents, such as statins, SGLT2 inhibitors, TRPML1 agonists, resveratrol, curcumin, and ferroptosis modulators (e.g., GLS1 activators and icariin), have demonstrated promise in restoring lysosomal function”

    Reviewin experimental models and early clinical settings

    Lysosomal Stress in Cardiovascular Diseases: Therapeutic Potential of Cardiovascular Drugs and Future Directions

    Biomedicines27 Apr 2025

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