Luteinizing hormone

1. Luteinizing hormone increases neurodegenerative disease states.

   “High concentrations of circulating follicle-stimulating hormone (FSH) and luteinizing hormone (LH) have shown to contribute to neurodegenerative disease states”

   Reviewhigh circulating concentrationsbrain

   The Hypothalamic-Pituitary-Ovarian Axis, Ovarian Disorders, and Brain Aging

   Endocrinology·30 Aug 2025

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1. Luteinizing hormone induces cellular senescence in mice.

   “LH causes ROS accumulation, calcium ion elevation and senescence in vibrissa follicles”

   Animalsvibrissa follicles

   Luteinizing Hormone Induces Murine Hair Loss through Transient Receptor Potential Canonical Channel-Mediated Cell Aging Responses: Implications for Female Pattern Hair Loss Pathogenesis

   The Journal of investigative dermatology·29 Apr 2025

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1. Luteinizing hormone induces hair loss in mice.

   “Hair loss in mice was due to LH-induced hair follicle damage and aging.”

   Animals

   Luteinizing Hormone Induces Murine Hair Loss through Transient Receptor Potential Canonical Channel-Mediated Cell Aging Responses: Implications for Female Pattern Hair Loss Pathogenesis

   The Journal of investigative dermatology·29 Apr 2025

1. Luteinizing hormone is associated with female pattern hair loss in humans.

   “Our results found a significant association between elevated LH levels and FPHL.”

   Humansin FPHL

   Luteinizing Hormone Induces Murine Hair Loss through Transient Receptor Potential Canonical Channel-Mediated Cell Aging Responses: Implications for Female Pattern Hair Loss Pathogenesis

   The Journal of investigative dermatology·29 Apr 2025

More on Female pattern hair loss