SATB1

Gene1 paper1 findingHGNC 10541MGI 105084NCBI Gene 6304Taxon 9606

  • Animals1

Effects

1

Chromatin and 3D genome organisation

downin mice1

1 study
  1. SATB1 protects against chromatin and 3D genome organisation in mice.

    Animalsshown by conditional deletion in naive T cellsnaive CD4+ T cells

    Loss of SATB1 alters 3D genome architecture in aged mouse T cells · Science advances · 2 Oct 2026

Chromatin and 3D genome organisation →

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 11
Science AdvancesAnimals

Loss of SATB1 alters 3D genome architecture in aged mouse T cells

Declining levels of the chromatin organizer SATB1 disrupt genomic boundaries and drive inflammatory gene activation in naive CD4+ T cells.Declining levels of the chromatin organizer SATB1 disrupt genomic boundaries and drive inflammatory gene activation in naive CD4+ T cells.