Osteophyte formation

2 papers

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Arthritis & RheumatologySep 22

MDL-800-induced SIRT6 activation decreases age-associated osteoarthritis in mice

Experiments in miceOsteoarthritis

DiagnosticsAug 27

Multiparametric CT-Based Adult Age Estimation Using Thoracic Vertebral Degenerative Changes, Vertebral Bone and Paraspinal Muscle Attenuation: A Regression-Based Approach

Cross-sectional study of 240 peopleBiomarkers

Journal of Oral & Facial Pain and HeadacheJun 1

Research progress on cellular senescence in the pathogenesis and treatment of osteoarthritis and temporomandibular joint osteoarthritis

ReviewCellular senescence

Ageing Research ReviewsApr 13

Age-associated regulation of chondrocyte hypertrophy in osteoarthritis: Mechanisms, therapeutic implications, and cartilage fate reprogramming

ReviewBones and joints

PhytomedicineMar 1

Pyrroloquinoline quinone alleviates age-related osteoarthritis via nuclear factor erythroid 2-related factor 2-mediated stress response and insulin-like growth factor 1 receptor upregulation

Experiments in miceKnee osteoarthritis

PhytomedicineFeb 21

Wogonin ameliorates osteoarthritis by targeting the STAT3/PIM1 axis to attenuate chondrocyte senescence

Experiments in miceOsteoarthritis

Cell CalciumJan 26

Basic calcium phosphate crystals aggravate senescence-related osteoarthritis through GPX4-NRF2-mediated ferroptosis

Experiments in ratsFerroptosis

AntioxidantsOct 29

The Influence of Sirtuin 6 on Chondrocyte Senescence in Osteoarthritis Under Aging: Focusing on Mitochondrial Dysfunction and Oxidative Stress

ReviewSirtuin signalling

International ImmunopharmacologyJun 11

Acetyl zingerone inhibits chondrocyte pyroptosis and alleviates osteoarthritis progression by promoting mitophagy through the PINK1/parkin signaling pathway

Experiments in micemTOR inhibitors

Cellular SignallingMay 1

SERPINF1 knockdown attenuates chondrocyte senescence, hypertrophy, and inflammation in osteoarthritis to offer a potential therapeutic strategy

Experiments in miceCellular senescence