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Metformin + tannic acid

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: China Postdoctoral Science Foundation and 5 more
  • Animals1

Outcomes

2

Osteoarthritis

downin rats1

1 study

  1. Metformin + tannic acid decreases osteoarthritis in rats.

    “intra-articular injection of NPs in rats with post-traumatic OA improves cartilage matrix degradation, osteophyte formation, and subchondral bone sclerosis over 8 weeks.”

    Animalsin rats with post-traumatic OAnanoparticles8 weeks

    Metformin-Loaded Tannic Acid Nanoparticles Attenuate Osteoarthritis by Promoting Chondrocyte Mitochondria Homeostasis Based on Mitocytosis

    BiomacromoleculesFeb 5, 2025

More on Osteoarthritis

Cellular homeostasis

upin rat cells1

1 study

  1. Metformin + tannic acid improves cellular homeostasis in rat cells.

    “enhanced mitocytosis to improve mitochondrial quality.”

    Cellsin OA's pathological environment

    Metformin-Loaded Tannic Acid Nanoparticles Attenuate Osteoarthritis by Promoting Chondrocyte Mitochondria Homeostasis Based on Mitocytosis

    BiomacromoleculesFeb 5, 2025

More on Cellular homeostasis

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