Late-onset Alzheimer's disease
Disease1 paper1 finding
- Humans1
Associations
1Hypothalamus volume
downin humans1
1 study
Hypothalamus volume
downin humans1
Late-onset Alzheimer's disease is associated with hypothalamus volume in humans (p < 0.010).
Humansin LOAD compared with EC
Different hypothalamic regions in late-onset Alzheimer's disease and aging: involvement and links with cognitive and non-cognitive features · GeroScience · 28 Aug 2026
Latest
8Genetic risk scores linked to faster progression to Alzheimer’s
In two observational cohorts, genetic scores were linked to faster progression to Alzheimer’s disease, with hazard ratios, a measure of risk over…In two observational cohorts, genetic scores were linked to faster progression to Alzheimer’s disease, with hazard ratios, a measure of risk over time, of 1.25 to 2.02.
Statins cut Alzheimer's risk but raise other dementia risks
A Mendelian randomization analysis found total cholesterol mediated 93.91% of statins' effect on overall dementia and 84.37% on dementia in…A Mendelian randomization analysis found total cholesterol mediated 93.91% of statins' effect on overall dementia and 84.37% on dementia in Alzheimer's disease.
APOE4 alters olfactory neurons across age and sex in mice
Whole-cell recordings in adult and aged humanized mice showed that APOE4 modified pyramidal cell and interneuron properties depending on both age and…Whole-cell recordings in adult and aged humanized mice showed that APOE4 modified pyramidal cell and interneuron properties depending on both age and sex.