Molecular Neurobiology·Nov 29Neuroprotective and Cognitive Benefits of a Ketogenic Diet in a Type 2 Diabetes Rat ModelExperiments in 7 ratsKetogenic dietPaper
The Journal of Nutrition·Nov 29Caloric Restriction Alleviates Anxiety-Like Behaviors by Mitigating Neuroinflammation and Insulin Signaling Dysregulation in a High-Fat Diet-Induced Obesity Mouse ModelExperiments in 24 miceDietary restrictionPaper
Physiology & Behavior·Nov 25Strain-specific behavioral, neuromolecular, and gut microbiota responses to aging and stress in rats with contrast nervous system excitabilityExperiments in ratsMicrobiome compositionPaper
bioRxiv·Nov 24The Christchurch point mutation in mouse APOE reduces Aβ-induced tau and α-synuclein pathologiesPreprint: experiments in miceAPOEPaper
NPJ Parkinson's Disease·Nov 23Depending on intensity, exercise improved or worsened pathology in a model of prodromal Parkinson's diseaseExperiments in animalsInterventionsPaper
Progress in Neuro-psychopharmacology & Biological Psychiatry·Nov 23Aging increases susceptibility to high-fat diet-induced neurobehavioral and mitochondrial dysfunction in zebrafishExperiments in zebrafishOxidative phosphorylationPaper
Biomedicine & Pharmacotherapy·Nov 13Evaluation of antidepressant and sleep-promoting effects of cordycepin in a menopause-like stress modelExperiments in ratsSleep disordersPaper
Brain, Behavior, & Immunity - Health·Nov 11Preventing effect of plant extracts and omega-3 on age-related cognitive decline in male miceExperiments in miceAge-related cognitive declinePaper
Archives of Gerontology and Geriatrics·Nov 8Exercise upregulates Mitsugumin 53 and ameliorates behavioral deficits and mitochondrial biogenesis in a sporadic Alzheimer's disease model in ratsExperiments in ratsTreadmill exercisePaper
Frontiers in Aging Neuroscience·Nov 7Stressors-induced cognitive dysfunction during aging: mechanisms and future challengesExperiments in miceOxidative phosphorylationPaper
Immunity & Ageing·Nov 5Ascorbic acid attenuates immunosenescence and cognitive decline via MYH9-Mediated CD8⁺ T cell differentiationExperiments in miceVitamin CPaper
Scientific Reports·Oct 29Ovariectomy attenuates phenotypes related to Alzheimer's disease in a preclinical mouse model and in C57BL/6 J miceExperiments in animalsMechanismsPaper
Physiology & Behavior·Oct 20Photobiomodulation enhances cognitive function in aging rats and modulates cytochrome c oxidase activity and c-Fos expression in memory-related circuitsExperiments in ratsInterventionsPaper
Experimental Neurology·Oct 15Lasmiditan ameliorates cortico-hippocampal pathology and improves cognition in aging parkinsonian miceExperiments in miceParkinson's diseasePaper
Brain and Behavior·Oct 10Antibiotic-Induced Gut Dysbiosis Modulates Alzheimer's Disease-Associated Gene Expression and Protein Aggregation in 3xTg-AD Mice via the Gut-Brain AxisExperiments in miceMicrobiome compositionPaper
Experimental Neurology·Oct 9Physical exercise protects neurons from energy deficit and improves cognitive function by upregulating astrocytic Slc2a1 in Alzheimer's diseaseExperiments in micePhysical exercisePaper
Brain, Behavior, and Immunity·Sep 30Cannabidiol attenuates diet-induced metabolic endotoxemia, neuroinflammation, and anxiety-like behaviors in male aged ratsExperiments in ratsAnxietyPaper
Journal of Neurodevelopmental Disorders·Aug 3Autism-like phenotype across the lifespan of Shank3B-mutant mice of both sexesExperiments in miceMechanismsPaper
Biological Psychiatry·Jul 31Urolithin A Abolishes High Anxiety and Rescues the Associated Mitochondria-Related Transcriptomic Signatures and Synaptic FunctionExperiments in ratsUrolithin APaper
GeroScience·Jul 16Nicotinamide riboside treatment enhances stress sensitivity and modulates hematological dynamics in aged miceExperiments in miceNicotinamide ribosidePaper
Nutrients·Jul 11Urolithin A Exhibits Antidepressant-like Effects by Modulating the AMPK/CREB/BDNF PathwayExperiments in miceUrolithin APaper
Brain and Behavior·Jul 11Behavioral Settings are Crucial for Assessing Sensorimotor, Anxiety, and Social Changes in Aging and Spinal Cord InjuryExperiments in miceAI & dataPaper
Molecular Neurobiology·Jul 8Pinocembrin Alleviates Postoperative Cognitive Dysfunction in Aged Mice by Modulating miR-384-5p/FZD1 Axis to Activate the Wnt/β-Catenin PathwayExperiments in micePostoperative cognitive dysfunctionPaper
Preprint·Jul 8Voluntary long-term exercise by female mice modulates anxiety-like behavior and motor function but minimally impacts acute oxidative injury in the central nervous systemPreprint: experiments in miceExercisePaper
Scientific Reports·Jul 2Sex-specific behavioral changes in middle-aged miceExperiments in miceMechanismsPaper
Behavioral and Brain Functions·Jun 16FTO (fat-mass and obesity-associated protein) deficiency aggravates age-dependent depression-like behaviors and cognitive impairmentExperiments in miceFTOPaper
mSystems·May 30Young gut microbiota transplantation improves the metabolic health of old miceExperiments in miceFecal microbiota transplantationPaper
Biogerontology·May 26The age-dependent impacts of treadmill exercise on cognitive impairments by reducing inflammation and oxidative stress in the hippocampus of morphine-exposed rats: the role of SIRTs 3 &4 and BDNFExperiments in 56 ratsTreadmill exercisePaper
Biological Trace Element Research·Mar 9Toxicological Alterations Induced by Subacute Exposure of Cobalt Oxide Nanoparticles in Aged Rats: Behavioral, Biochemical, Molecular, and Histopathological EvidenceExperiments in ratsMechanismsPaper
bioRxiv·Mar 3The 5-HT1F Receptor Agonist Lasmiditan improves Cognition and Ameliorates Associated Cortico-Hippocampal Pathology in Aging Parkinsonian MicePreprint: experiments in miceParkinson's diseasePaper