Biochemical and Biophysical Research Communications
Gene deletion reduced brain inflammation in aged mice
In animal experiments, aged mice lacking the gene also showed better motor function and less anxiety-like behavior than mice with the gene intact.In animal experiments, aged mice lacking the gene also showed better motor function and less anxiety-like behavior than mice with the gene intact.
Mouse studyInflammation
Who was studiedAged xCTKO mice, against aged wild-type mice
What changedTNF-α protein expression in the brain was lower in aged xCTKO mice than in aged wild-type mice
The catchBrain inflammation was measured by TNF-α protein, but TNF-α mRNA levels remained elevated