Blood flow in one brain region rose by 4.9 millilitres per 100 grams per minute more with spermidine than placebo over 12 months.Blood flow in one brain region rose by 4.9 millilitres per 100 grams per minute more with spermidine than placebo over 12 months.
Young and 18-month-old mice with an altered UCHL1 protein showed less white matter injury and better sensorimotor and cognitive performance in a dementia model.Young and 18-month-old mice with an altered UCHL1 protein showed less white matter injury and better sensorimotor and cognitive performance in a dementia model.
Neutrophil-coated nanoparticles crossed the blood-brain barrier, altered microglial metabolism, and improved cognitive performance after surgery in older mice.Neutrophil-coated nanoparticles crossed the blood-brain barrier, altered microglial metabolism, and improved cognitive performance after surgery in older mice.
In 48,645 UK Biobank participants, plasma proteomic profiles linked ambient air pollutants to mortality and chronic diseases through shared immune and divergent molecular…In 48,645 UK Biobank participants, plasma proteomic profiles linked ambient air pollutants to mortality and chronic diseases through shared immune and divergent molecular pathways.