Exosomes
Intervention4 papers4 findings
A review describes exosomes activating PI3K–AKT signalling and Wnt/β-catenin signalling, as well as inducing angiogenesis.
Outcomes
4Angiogenesis
upin reviews1
1 study
Angiogenesis
upin reviews1
Exosomes induce angiogenesis.
Review
Exosomes: The Elixir or the Trojan Horse · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 1 Oct 2026
PI3K–AKT signalling
upin reviews1
1 study
PI3K–AKT signalling
upin reviews1
Exosomes activate PI3K–AKT signalling.
Review
Exosomes: The Elixir or the Trojan Horse · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 1 Oct 2026
Wnt/β-catenin signalling
upin reviews1
1 study
Wnt/β-catenin signalling
upin reviews1
Exosomes activate wnt/β-catenin signalling.
Review
Exosomes: The Elixir or the Trojan Horse · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 1 Oct 2026
Ovarian regeneration
upin humans1
1 study
Ovarian regeneration
upin humans1
Exosomes improve ovarian regeneration in humans.
Reviewovarian aging
Evaluating the Role of Exosome Therapy in Reproductive Aging:A Narrative Review of Recent Advancements · Current health sciences journal · 30 Jun 2026
Trials
11In trials
Phase 4 · Completed · 1 trial
Phase 1/2 · Recruiting · 1 trial
Intervertebral disc degeneration
Phase 1 · Completed · 1 trial
Trial sponsors
Company1 trialEarly phase 116 people
Instituto de Oftalmología Fundación Conde de Valenciana
1 trialPhase 430 people
Affiliated Hospital of Nantong University
1 trialPhase 230 people
Peking University First Hospital
1 trialPhase 1/266 people
Dr. Himanshu Bansal Foundation
1 trialPhase 130 people
1 trialPhase 118 people
1 trialPhase 110 people
The First Affiliated Hospital of Xinxiang Medical College
2 trialsEarly phase 1216 people
Funding
National Institute on AgingUS$2.9mNational Heart, Lung, and Blood InstituteUS$744.1k5 grants since 2017
Cell-drones: engineered stem cell nanovesicles as alternatives to exosomes
National Heart, Lung, and Blood InstituteTexas A&m University Health Science CtrUS$379.2k2024–2028
Pathogenic exosomes during herpes zoster mediate increased vascular dementia risk
National Institute on AgingUniversity of Colorado, DenverUS$1.9m2024–2029
Stem Cell-Derived Exosomes, MrgD and Vascular Cognitive Impairment in Aging
National Institute on AgingNorth Dakota State UniversityUS$442.4k2017–2028
Nanowired humam cardiac organoid derived exosomes for heart repair
National Heart, Lung, and Blood InstituteClemson UniversityUS$364.9k2023–2027
The role of oral microbially induced exosomes in Alzheimer's disease pathogenesis
National Institute on AgingAugusta UniversityUS$555.2k2025–2029