Acromegaly
- Humans4
- Animals1
Associations
9Frailty
upin humans1OR 3
1 study
Frailty
upin humans1OR 3
Acromegaly is associated with frailty in humans (OR = 3.00, p = 0.076).
“acromegaly showed a borderline trend (OR = 3.00, p = 0.076).”
Humanscompared to healthy controls
Journal of clinical medicine
Prostate cancer
upin humans1OR 1.49
1 study
Prostate cancer
upin humans1OR 1.49
Acromegaly raises the risk of prostate cancer in humans (OR 1.49, 95% CI 1.25-1.77).
“prostate cancer (OR 1.49, 95% CI 1.25-1.77)”
Humans
ENDO 2025 abstract
Lung cancer
upin humans1OR 1.85
1 study
Lung cancer
upin humans1OR 1.85
Acromegaly raises the risk of lung cancer in humans (OR 1.85, 95% CI 1.51-2.27).
“lung cancer (OR 1.85, 95% CI 1.51-2.27)”
Humans
ENDO 2025 abstract
Breast cancer
upin humans1OR 1.78
1 study
Breast cancer
upin humans1OR 1.78
Acromegaly raises the risk of breast cancer in humans (OR 1.78, 95% CI 1.54-2.06).
“breast cancer (OR 1.78, 95% CI 1.54-2.06)”
Humans
ENDO 2025 abstract
Ovarian cancer
upin humans1OR 1.89
1 study
Ovarian cancer
upin humans1OR 1.89
Acromegaly raises the risk of ovarian cancer in humans (OR 1.89, 95% CI 1.30-2.76).
“ovarian cancer (OR 1.89, 95% CI 1.30-2.76)”
Humans
ENDO 2025 abstract
Leukemia/lymphoma
upin humans1OR 3.32
1 study
Leukemia/lymphoma
upin humans1OR 3.32
Acromegaly raises the risk of leukemia/lymphoma in humans (OR 3.32, 95% CI 2.35-4.69).
“Acromegaly patients had a significantly higher prevalence of cancer, including leukemia/lymphoma (OR 3.32, 95% CI 2.35-4.69”
Humans
ENDO 2025 abstract
Metabolic disorders
upin humans1OR 4.1
1 study
Metabolic disorders
upin humans1OR 4.1
Acromegaly raises the risk of metabolic disorders in humans (OR 4.1, 95% CI 2-8.3, p = 0.006).
“and metabolic disorders (p = 0.006, OR: 4.1 95%IC: 2-8.3)”
Humanselderly acromegaly vs controlsn = 189
Endocrine
Left ventricular hypertrophy
upin humans1OR 3
1 study
Left ventricular hypertrophy
upin humans1OR 3
Acromegaly raises the risk of left ventricular hypertrophy in humans (OR 3, 95% CI 1.5-5.8, p = 0.01).
“left ventricular hypertrophy (p = 0.01, OR: 3 95%IC: 1.5-5.8)”
Humanselderly acromegaly vs controlsn = 189
Endocrine
Arterial hypertension
upin humans1OR 5.4
1 study
Arterial hypertension
upin humans1OR 5.4
Acromegaly raises the risk of arterial hypertension in humans (OR 5.4, 95% CI 2.6-10.9, p < 0.001).
“elderly-ACRO had an increased risk for the occurrence of systemic arterial hypertension (p < 0.001, OR: 5.4 95%IC:2.6-10.9)”
Humanselderly acromegaly vs controlsn = 189
Endocrine
Trial sponsors
Novartis Pharmaceuticals Corporation
Company1 trialPhase 4249 people
Funding
1 grant since 2018National Institute of Diabetes and Digestive and Kidney DiseasesUS$1.8m