Transcriptional remodeling

Biomarker

1 paper

  • In silico1

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bioRxiv

Voluntary running shows limited neuroprotection in mice

In 5xFAD mice, 16 weeks of voluntary wheel running altered fat tissue but produced modest hippocampal changes and failed to improve amyloid pathology or memory.In 5xFAD mice, 16 weeks of voluntary wheel running altered fat tissue but produced modest hippocampal changes and failed to improve amyloid pathology or memory.

Preprint: experiments in miceInterventions
Aging Cell

Autophagy flux varies by sex and cell type during human aging

In older adults, higher autophagy flux in blood cells linked to lower physical function and decreased after a 12-week exercise intervention.In older adults, higher autophagy flux in blood cells linked to lower physical function and decreased after a 12-week exercise intervention.

Cohort study in peopleAutophagy