bioRxiv
Model suggests how cell behavior shapes lung scarring in aged mice
In aged-mouse simulations, cell contact expanded senescent cell numbers, while the timing of their removal by immune cells shaped lung scarring.In aged-mouse simulations, cell contact expanded senescent cell numbers, while the timing of their removal by immune cells shaped lung scarring.
Preprint: computational studyLung
Who was studiedSimulated lung fibroblasts in aged mice
What changedContact between senescent and non-senescent fibroblasts increased senescent cell numbers in aged-mouse simulations
The catchTwo-dimensional geometry could distort contact rates between senescent and non-senescent fibroblasts