Increased Plasma Amyloid and Tau Concentrations associated with Decreased Mechanical Integrity of Braak Regions Measured with Magnetic Resonance Elastography

Abstract

Background: Up to two‐thirds of adults with Alzheimer's Disease (AD) biological pathology, including amyloid and tau accumulations, may remain asymptomatic. This asymptomatic stage of pathology may represent a crucial window for therapeutic intervention before the onset of clinical symptoms.