Thioredoxin

Biomarker

3 papers1 finding

MeSH

  • Animals2

Interventions

1

Caloric restriction

downin rats1

1 study
  1. Caloric restriction prevents thioredoxin in rats.

    “while Trx and Trx reductase (TrxR) in cytoplasm decrease with age in AL-fed rats, CR prevents these decreases”

    Animalsduring agingkidney

    Modulation of glutathione and thioredoxin systems by calorie restriction during the aging process

    Experimental gerontology1 May 2003

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Antioxidants & Redox Signaling

Protein loss caused senescence-like changes in lab-grown neurons

Experiments in models of neurons that regulate energy balance found cell enlargement and other senescence-like changes after researchers removed or reduced selenoprotein…Experiments in models of neurons that regulate energy balance found cell enlargement and other senescence-like changes after researchers removed or reduced selenoprotein T.

Experiments in miceCellular senescence
Redox Biology

Ferroptosis inducers shorten lifespan in fruitflies

Erastin and RSL3 shortened survival dose-dependently, an effect rescued by ferrostatin-1, while altering iron and lipid profiles selectively in males.Erastin and RSL3 shortened survival dose-dependently, an effect rescued by ferrostatin-1, while altering iron and lipid profiles selectively in males.

Experiments in fliesFerroptosis