Systemic inflammation

Biomarker

3 papers2 findings

  • Humans1
  • Animals2

Interventions

1

Physical activity

downin humans1

1 study
  1. Physical activity decreases systemic inflammation in humans.

    “PA is dose-dependently associated with lower levels of systemic inflammation.”

    Humans

    Physical activity decreases cancer burden by alleviating immunosenescence-related inflammation and improving overall immunity

    Cell reports. Medicine16 Dec 2025

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Upstream

1

ANGPTL2DEFICIENCY

downin mice1

1 study
  1. ANGPTL2DEFICIENCY decreases systemic inflammation in mice.

    “ANGPTL2 deficiency shortened lifespan but attenuated systemic inflammation”

    Animalshigh-fat diet-induced premature aging

    Context-Dependent Roles of ANGPTL2-Mediated Inflammaging in Tissue Homeostasis, Pathological Tissue Remodeling, and Longevity

    Aging cell9 Jan 2026

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Exploration

Bazi Bushen eased stress-induced signs of aging in mice

A 12-month chronic stress experiment in mice found that the compound medicine eased signs of aging and reduced inflammation across several tissues.A 12-month chronic stress experiment in mice found that the compound medicine eased signs of aging and reduced inflammation across several tissues.

Experiments in miceInterventions
Research Square

Blood-cell telomerase delays premature aging in zebrafish

Boosting telomerase in blood-forming cells extended lifespan in immune-deficient zebrafish and partly restored gut health, operating without major changes in telomere…Boosting telomerase in blood-forming cells extended lifespan in immune-deficient zebrafish and partly restored gut health, operating without major changes in telomere length.

Preprint: experiments in zebrafishTelomerase and telomere maintenance
bioRxiv

Caloric restriction delays cancer wasting in mice

In a mouse model of lung cancer, restricting food before tumour induction preserved lean mass and prolonged survival where targeting individual candidate factors failed.In a mouse model of lung cancer, restricting food before tumour induction preserved lean mass and prolonged survival where targeting individual candidate factors failed.

Preprint: experiments in miceDietary restriction