Senescence-associated secretory phenotype factors

6 papers

Animals3

Funding

1 grant since 2022

Japan Society for the Promotion of ScienceJP¥4.2m

Elucidation of molecular mechanisms of sarcopenia based on the regulation of senescence-associated secretory phenotype factors
Japan Society for the Promotion of ScienceUniversity of TokyoJP¥4.2m2022–2025

Latest

29 in 12 months

FASEB Journal23 Sep

ADP Inhibits Macrophage Senescence via the AMPK/KLF10 Pathway in Systemic Lupus Erythematosus

Experiments in miceAMPK signalling

The Journal of Nutrition19 Sep

Schisandra chinensis Modulates Cellular Senescence through Integrated Regulation of Redox, Mitochondrial, and Inflammatory Homeostasis

ReviewInterventions

Frontiers in Medicine18 Sep

Necroptosis-senescence crosstalk in tubulointerstitial fibrosis: the mtDNA-cGAS-STING-PFKFB3 axis as a metabolic bridge

ReviewMechanisms

Frontiers in Endocrinology8 Sep

Senescent immune cells, inflammaging, and bone loss: therapeutic potential and translational challenges of senolytics in osteoporosis

ReviewSenolytics

Life Medicine28 Aug

A framework of biomarkers for renal aging: a consensus statement by the Aging Biomarker Consortium

CommentaryBiomarkers

Experimental Neurology17 Aug

Pathological α-synuclein propagation via the gut-liver axis induces liver injury in gut-origin Parkinson's disease mouse models

Experiments in miceGut and microbiome

PNAS21 Jul

Single-cell atlas of the mouse ovary reveals molecular drivers of aging and senescence during the estropausal transition

Experiments in miceSingle-cell omics

Experimental Neurology11 Jul

Microglia-astrocyte crosstalk-driven metabolic-inflammatory imbalance and cerebrovascular frailty in exacerbating stroke injury during aging

ReviewInflammation

Molecular Cell30 May

Mitochondria-lysosome coupling contributes to lysosome acidification and aging

Experiments in cellsMechanisms

Menopause5 May

Biological markers of aging across the menopause transition: current evidence

ReviewMenopause