Experiments in mice with impaired DNA repair identified a female-specific metabolic pathway; a dietary supplement restored muscle force and metabolic profiles in females.Experiments in mice with impaired DNA repair identified a female-specific metabolic pathway; a dietary supplement restored muscle force and metabolic profiles in females.
The peptide also boosted maturation and fertilization in aged human oocytes by activating the vitamin B6 and VEGF pathway.The peptide also boosted maturation and fertilization in aged human oocytes by activating the vitamin B6 and VEGF pathway.
A genome-scale screen in retinal cells identified NKX2-5 variants that conferred oxidative resilience and improved physical function without detectable toxicity.A genome-scale screen in retinal cells identified NKX2-5 variants that conferred oxidative resilience and improved physical function without detectable toxicity.
Restoring the fatty acid reversed visual decline in mice and cleared toxic oxidized lipids that otherwise trigger chronic microglial activation.Restoring the fatty acid reversed visual decline in mice and cleared toxic oxidized lipids that otherwise trigger chronic microglial activation.
Inhibiting the proteasome accelerates ATP depletion, protein aggregation, and clearance markers in stored and aged red blood cells.Inhibiting the proteasome accelerates ATP depletion, protein aggregation, and clearance markers in stored and aged red blood cells.