Liver triglycerides

Biomarker

2 papers3 findings

  • Animals2

Interventions

2

Semaglutide + exercise

downin rats1

1 study
  1. Semaglutide + exercise decreases liver triglycerides in rats.

    “This combined treatment reduced HDL levels, hepatic triglycerides and scWAT relative weight.”

    Animalsin ovariectomized ratsfour weeksfemales

    Metabolic effects of a GLP-1 analog combined with aerobic training in ovariectomized rats

    Molecular and cellular endocrinology11 Sep 2026

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Exercise

downin rats1

1 study
  1. Exercise decreases liver triglycerides in rats.

    “EXE decreased total and LDL cholesterol, liver triglycerides and HSF1 expression in both tissues”

    Animalsin ovariectomized ratsfour weeksfemales

    Metabolic effects of a GLP-1 analog combined with aerobic training in ovariectomized rats

    Molecular and cellular endocrinology11 Sep 2026

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Upstream

1

SHC1

no changein mice1

1 study
  1. SHC1 has no effect on liver triglycerides in mice.

    “p46Shc overexpression did not significantly change liver triglycerides.”

    Animalsp46Shc overexpressionliver

    P46Shc Inhibits Mitochondrial ACAA2 Thiolase, Exacerbating Mitochondrial Injury and Inflammation in Aging Livers

    The American journal of pathology20 Dec 2024

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