BAM15
- 1 lab in 1 country
- Funders: National Center for Complementary and Integrative Health and 3 more
- Animals2
- Model organisms1
Outcomes
3Oxidative phosphorylation
upin flies1
1 study
Oxidative phosphorylation
upin flies1
BAM15 increases oxidative phosphorylation in flies.
“BAM15 enhanced oxidative phosphorylation capacity supported by pyruvate + malate, proline, and glycerol 3-phosphate.”
Model organismsflight muscle
Aging cell11 Feb 2024
Locomotor activity
upin flies1+125%
1 study
Locomotor activity
upin flies1+125%
BAM15 improves locomotor activity in flies (+125%).
“improved locomotor activity by 125% on ND and 53% on HFD”
Model organismsnormal diet
Aging cell11 Feb 2024
Lifespan
upin flies1+9%
1 study
Lifespan
upin flies1+9%
BAM15 extends lifespan in flies (+9%).
“BAM15 extended life span by 9% on ND and 25% on HFD”
Model organismsnormal diet
Aging cell11 Feb 2024
Latest
1 in 12 monthsPreprints.org
Rescuing Healthspan in Obese, Aged Mice: A Comparison between Multi-Ingredient Nutraceuticals and Senolytic Interventions
Preprint: experiments in miceInterventions
Molecular Metabolism
Diverse actions of 15 structurally unrelated mitochondrial uncouplers in cells and mice
Experiments in animalsInterventions
bioRxiv
Comparable anti-ageing efficacies of a multi-ingredient nutraceutical and a senolytic intervention in old mice
Preprint: experiments in miceSenolytics
Aging Biology
Mild Uncoupling of Mitochondria Synergistically Enhances Senolytic Specificity and Sensitivity of BH3 Mimetics
Experiments in miceSenolytics