INTERLEUKIN-8

1. INTERLEUKIN-8 predicts gastric cancer in humans (adjusted HR 6.94, p < 0.001).

   “Baseline IL-8 > 52.3 pg/mL was independently associated with progression (adjusted HR: 6.94, p < 0.001)”

   Humansprogression from precancerous lesions24 monthsn = 94

   Serial serum interleukin-8 trajectories are associated with progression from Helicobacter pylori-associated precancerous lesions to gastric cancer: a prospective longitudinal cohort study · Gut pathogens · 23 Sep 2026

2. INTERLEUKIN-8 raises the risk of gastric cancer in humans (aOR 2.31 per 10 pg/mL, 95% CI 1.48-3.61).

   “baseline IL-8 (aOR per 10 pg/mL: 2.31, 95% CI: 1.48-3.61”

   Humansin patients with H. pylori-associated precancerous lesions24 monthsn = 94

   Serial serum interleukin-8 trajectories are associated with progression from Helicobacter pylori-associated precancerous lesions to gastric cancer: a prospective longitudinal cohort study · Gut pathogens · 23 Sep 2026

Gastric cancer →