Inflammatory macrophages

Biomarker

1 paper

  • Animals1

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Dysferlin promotes inflammatory macrophage responses in cells

In cellular models, dysferlin promoted inflammatory macrophage responses, and dysferlin-enriched macrophages suppressed muscle cell differentiation and fusion in…In cellular models, dysferlin promoted inflammatory macrophage responses, and dysferlin-enriched macrophages suppressed muscle cell differentiation and fusion in co-culture.

Experiments in human cellsInflammation
bioRxiv

Exercise remodels muscle progenitor cells in older adults

Six weeks of blood flow restricted resistance exercise enlarged muscle progenitor cells and shifted fibro-adipogenic progenitors toward a pro-myogenic state in healthy…Six weeks of blood flow restricted resistance exercise enlarged muscle progenitor cells and shifted fibro-adipogenic progenitors toward a pro-myogenic state in healthy older adults.

Preprint: non-randomised trial in peopleResistance training
International Journal of Molecular Sciences

Activin A is linked to muscle stem cell shifts in human ageing

Transcriptomic profiling of human skeletal muscle paired with cell experiments identified inflammatory macrophages and Activin A signaling as candidate regulators of…Transcriptomic profiling of human skeletal muscle paired with cell experiments identified inflammatory macrophages and Activin A signaling as candidate regulators of altered muscle stem cells.

Cohort study in peopleMuscle