Functional dependency

Biomarker

2 papers

  • Humans2

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Mechanisms of Ageing and Development

Resveratrol reversed some toxin effects in lab-grown liver cells

Experiments in human and pig liver cells found that resveratrol’s ability to reverse toxin-induced changes depended on the species and liver function measured.Experiments in human and pig liver cells found that resveratrol’s ability to reverse toxin-induced changes depended on the species and liver function measured.

Experiments in human cellsResveratrol
bioRxiv

Tool maps spatial cell-cell signals in brain aging and cancer

Applied to over 5.8 million spatially profiled cells, the framework identified a T-cell-associated brain-aging program and signals that predicted age across regions.Applied to over 5.8 million spatially profiled cells, the framework identified a T-cell-associated brain-aging program and signals that predicted age across regions.

Preprint: computational studyAI & data
Aging Cell

Autophagy flux varies by sex and cell type during human aging

In older adults, higher autophagy flux in blood cells linked to lower physical function and decreased after a 12-week exercise intervention.In older adults, higher autophagy flux in blood cells linked to lower physical function and decreased after a 12-week exercise intervention.

Cohort study in peopleAutophagy
Archives of Gerontology and Geriatrics

Calf size and physical function predict heart failure mortality

In 7,362 older patients hospitalized with heart failure, combining physical performance scores with calf circumference stratified one-year mortality risk across cohorts.In 7,362 older patients hospitalized with heart failure, combining physical performance scores with calf circumference stratified one-year mortality risk across cohorts.

Cohort study of 7,362 peopleHeart failure