Cognitive impairment

Biomarker

1 paper1 finding

  • Humans1

Associations

1

Mortality

upin humans1HR 1.29

1 study
  1. Cognitive impairment raises the risk of mortality in humans (HR 1.29 (95% CI: 1.06-1.56)).

    Humansmild cognitive impairment, adjusted for potential confounding factors including social engagement15-yearmalesn = 1,741

    Cognitive function predicts all-cause mortality independent of social engagement among community-dwelling elderly Japanese men: a 15-year prospective cohort study

    Environmental health and preventive medicine1 Jan 2026

Funding

2 grants since 2017

National Institute on AgingUS$525.4k

Latest

Nov 2025: 11Dec 2025: 939Jan 2026: 103Feb 2026: 1Mar 2026: 1Apr 2026: 1May 2026: 2Jun 2026: 13Jul 2026: 53Aug 2026: 287Sep 2026: 326Oct 2026: 741,811 in 12 months
bioRxiv

Models link brain network organisation to local changes in aging

An observational analysis of an aging cohort linked local connection patterns to highly connected hubs, nearby connections and groups of connected brain regions.An observational analysis of an aging cohort linked local connection patterns to highly connected hubs, nearby connections and groups of connected brain regions.

Preprint: study in peopleMechanisms
Nature Neuroscience

Genetic data highlight potential drug targets for Alzheimer's

A Mendelian randomisation analysis identified 19 candidate targets in people of European ancestry and seven in people of African ancestry.A Mendelian randomisation analysis identified 19 candidate targets in people of European ancestry and seven in people of African ancestry.

Mendelian randomisation in 111,680 peopleAlzheimer's disease