Extracellular matrix remodeling-associated transcriptional module

Biomarker

1 paper1 finding

  • Animals1

Interventions

1

Rlx@pnac4a

upin mice1

1 study
  1. Rlx@pnac4a activates extracellular matrix remodeling-associated transcriptional module in mice.

    “RLX@PnAC4A activated a dominant, therapy-specific transcriptional module enriched in extracellular matrix remodeling and pro-regenerative signaling”

    Animalsovariectomized mice

    Bone-targeted drug delivery improves bone structure in mice

    Materials today. Bio23 Sep 2026

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Materials Today Bio

Bone-targeted drug delivery improves bone structure in mice

In mice lacking ovaries, the targeted carrier delivered raloxifene to bone tissue and improved bone formation and structural integrity compared with the free drug.In mice lacking ovaries, the targeted carrier delivered raloxifene to bone tissue and improved bone formation and structural integrity compared with the free drug.

Experiments in miceBones and joints