Drp1 expression

1 paper studies it17 more mention it

Animals1

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4 papers in 12 months

BiogerontologyJul 28

AGGF1 delays endothelial cellular senescence through the TGFB3-TAK1-AMPK signaling axis

Experiments in human cellsAMPK signaling

Biology DirectMay 30

Inhibiting the Hif-1α-Drp1 axis alleviates mitochondrial dysfunction and reduces senescence-like changes in myocardial tissue after acute myocardial infarction

Experiments in ratsCellular senescence

Life SciencesMar 21

Placental dysregulation of mitochondrial morphology and dynamics as a hallmark of maternal age-related adaptation

Cohort study in peopleMitochondrial fission and fusion

Military Medical ResearchDec 1

β-catenin initiates peritoneal fibrosis by triggering mitochondrial fission-mediated mesothelial cell senescence fate transition

Study in peopleInterventions

Biochemical PharmacologyAug 24

Aging as a critical factor in chronic oxaliplatin-induced neuropathy: Protective effects of 7-chloro-4-(phenylselanyl) quinoline through modulation of NF-κB and Drp1 expression, and platinum distribution

Experiments in ratsPeripheral neuropathy

Redox BiologyAug 19

DRP1 downregulation impairs mitophagy, driving mitochondrial ROS and SASP production in rheumatoid arthritis CD4⁺PD-1⁺T cells

Study in peopleMitophagy

BiogerontologyJan 7

Age and dietary restriction modulate mitochondrial quality in quadriceps femoris muscle of male mice

Experiments in miceDietary restriction

Redox BiologyJul 31

Epigenetic modulation of Drp1-mediated mitochondrial fission by inhibition of S-adenosylhomocysteine hydrolase promotes vascular senescence and atherosclerosis

Experiments in miceMitochondrial fission and fusion

Lipids in Health and DiseaseMar 7

Exercise activates Sirt1-mediated Drp1 acetylation and inhibits hepatocyte apoptosis to improve nonalcoholic fatty liver disease

Experiments in ratsAerobic exercise

Applied Physiology, Nutrition, and MetabolismFeb 15

The role of the mechanistic target of rapamycin complex 1 in the regulation of mitochondrial adaptation during skeletal muscle atrophy under denervation or calorie restriction in mice

Experiments in miceDietary restriction