DNA damage accumulation

Biomarker

2 papers1 finding

Animals1
Model organisms1

Interventions

Dihydrotestosterone

downin mice1

1 study

Dihydrotestosterone decreases DNA damage accumulation in mice.
“DHT administration reduces DNA damage accumulation and promotes structural and functional recovery in HGPS hearts.”
Animalsin HGPS miceheart
DHT ameliorates cardiac aging in progeroid mice by XRCC4-mediated genome stabilization
Mechanisms of ageing and development3 Dec 2025

Latest

16 in 12 months

Ageing Research Reviews7 Oct

Vascular Aging-Driven Tumor-Like Transformation of Vascular Smooth Muscle Cells in Atherosclerotic Cardiovascular Disease: Mechanisms and Therapeutic Targets

ReviewMechanisms

Paper

Research Square7 Oct

DNA damage differed by sex in mice with impaired DNA repair

Experiments in mice with impaired DNA repair identified a female-specific metabolic pathway; a dietary supplement restored muscle force and metabolic profiles in females.Experiments in mice with impaired DNA repair identified a female-specific metabolic pathway; a dietary supplement restored muscle force and metabolic profiles in females.

Preprint: experiments in miceDNA repair

Paper

Frontiers in Medicine2 Sep