Induced protein production reduced frailty progression by 44% in aged mice and was associated with a 14% extension of median lifespan.Induced protein production reduced frailty progression by 44% in aged mice and was associated with a 14% extension of median lifespan.
In an animal experiment, 18-month-old mice given the compound for 28 days also showed better spatial memory, without changes in movement.In an animal experiment, 18-month-old mice given the compound for 28 days also showed better spatial memory, without changes in movement.
A computational analysis of single-cell gene activity data predicted increasingly different responses to disrupting the same gene at older ages.A computational analysis of single-cell gene activity data predicted increasingly different responses to disrupting the same gene at older ages.
An observational study of COVID-19 survivors aged 18–59 and 60 or older found weaker responses after inactivated vaccines and subsequent Omicron infection in older…An observational study of COVID-19 survivors aged 18–59 and 60 or older found weaker responses after inactivated vaccines and subsequent Omicron infection in older adults.
In experiments, aged mice lacking the protein showed stronger age-linked brain cell activation, but no obvious loss of nerve insulation or faster decline in movement.In experiments, aged mice lacking the protein showed stronger age-linked brain cell activation, but no obvious loss of nerve insulation or faster decline in movement.