Sus scrofa
Organism4 papers7 findingsTaxon 9823
- Animals2
- Cells1
Interventions
3Leptin
upautophagy1downcellular senescence1downgenomic instability1upMAPK/ERK signalling1+1
1 study
Leptin
upautophagy1downcellular senescence1downgenomic instability1upMAPK/ERK signalling1+1
Leptin decreases senescence-associated beta-galactosidase in pig cells.
Cellsunder heat stressSertoli cellmales
Leptin mitigates heat stress-induced senescence in porcine Sertoli cells through modulation of ATM-p53, ERK1/2, and AMPK-mTORC1 signaling · Journal of animal science · 26 Sep 2026
Leptin activates autophagy in pig cells.
Cellsunder heat stressSertoli cellmales
Leptin mitigates heat stress-induced senescence in porcine Sertoli cells through modulation of ATM-p53, ERK1/2, and AMPK-mTORC1 signaling · Journal of animal science · 26 Sep 2026
Leptin activates MAPK/ERK signalling in pig cells.
Cellsunder heat stressSertoli cellmales
Leptin mitigates heat stress-induced senescence in porcine Sertoli cells through modulation of ATM-p53, ERK1/2, and AMPK-mTORC1 signaling · Journal of animal science · 26 Sep 2026
Leptin decreases genomic instability in pig cells.
Cellsunder heat stressSertoli cellmales
Leptin mitigates heat stress-induced senescence in porcine Sertoli cells through modulation of ATM-p53, ERK1/2, and AMPK-mTORC1 signaling · Journal of animal science · 26 Sep 2026
Leptin decreases cellular senescence in pig cells.
Cellsunder heat stressSertoli cellmales
Leptin mitigates heat stress-induced senescence in porcine Sertoli cells through modulation of ATM-p53, ERK1/2, and AMPK-mTORC1 signaling · Journal of animal science · 26 Sep 2026
Heat stress
upcellular senescence1
1 study
Heat stress
upcellular senescence1
Heat stress induces cellular senescence in pig cells.
CellsSertoli cellmales
Leptin mitigates heat stress-induced senescence in porcine Sertoli cells through modulation of ATM-p53, ERK1/2, and AMPK-mTORC1 signaling · Journal of animal science · 26 Sep 2026
ANTI-MIR-128 aso
downDuchenne muscular dystrophy1
1 study
ANTI-MIR-128 aso
downDuchenne muscular dystrophy1
ANTI-MIR-128 aso protects against Duchenne muscular dystrophy in pigs.
Animalspig model of Duchenne muscular dystrophyantisense oligonucleotidestriated muscle
Inhibiting miR-128-3p restores muscle mass and function in aged mice · bioRxiv : the preprint server for biology · 7 Sep 2026 · Preprint
Latest
4Inhibiting miR-128-3p restores muscle mass and function in aged mice
The microRNA inhibitor also improved cardiac outcomes after infarction and reduced pathology in mouse and pig models of muscular dystrophy.
bioRxiv : the preprint server for biology · Boldridge MA et al.
Macrophage CD38 drives age-related placental senescence by depleting NAD+
Targeting CD38 or supplementing NAD+ precursors reduces placental aging and improves offspring metabolic health in models of delayed maternal age.
Nature communications · Hua L et al.