ANTI-MIR-128 aso

Intervention1 paper3 findings

Outcomes

Duchenne muscular dystrophy

downin mice1downin pigs1

1 study

ANTI-MIR-128 aso protects against Duchenne muscular dystrophy in pigs.
Animalspig model of Duchenne muscular dystrophyantisense oligonucleotidestriated muscle
Inhibiting miR-128-3p restores muscle mass and function in aged mice · bioRxiv : the preprint server for biology · 7 Sep 2026 · Preprint
ANTI-MIR-128 aso protects against Duchenne muscular dystrophy in mice.
Animalsmouse model of Duchenne muscular dystrophyantisense oligonucleotidestriated muscle
Inhibiting miR-128-3p restores muscle mass and function in aged mice · bioRxiv : the preprint server for biology · 7 Sep 2026 · Preprint

Physical function

upin mice1

1 study

ANTI-MIR-128 aso improves physical function in mice.
Animalsfollowing myocardial infarctionantisense oligonucleotideheart
Inhibiting miR-128-3p restores muscle mass and function in aged mice · bioRxiv : the preprint server for biology · 7 Sep 2026 · Preprint

AnimalsPreprintMitochondria5 h

The microRNA inhibitor also improved cardiac outcomes after infarction and reduced pathology in mouse and pig models of muscular dystrophy.

bioRxiv : the preprint server for biology · Boldridge MA et al.