Tacrolimus

Intervention4 papers2 findingsPubChem 445643ChEBI 61049MeSH D016559

  • Humans2
  • Animals1

Outcomes

2

Mortality

downin humans1HR 0.18Moderate certainty

1 study
  1. Tacrolimus decreases mortality in humans (HR 0.18, 95% CI 0.05-0.66, p = 0.009).

    Humanscompared with cyclosporine in KTRs

    Fracture incidence and mortality in kidney transplant recipients compared with waitlisted dialysis patients: A single-center retrospective analysis · Clinical nephrology · 8 Sep 2026

Graft survival

upin Papio1Very low certainty

1 study
  1. Tacrolimus improves graft survival in Papio (up to 675 days).

    Animalswith anti-CD2, anti-CD154, and belataceptn = 7

    Flow Cytometric Immune Profiling Enables Early Detection of Rejection in Islet Xenotransplantation · Xenotransplantation · 1 Jan 2026

Funding

National Institute on AgingUS$915.2k1 grant since 2017

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