Papers on opioid

312 papers13 new in 30 days

Sunday, October 25

BMJ OpenOct 25

Cannabis legalisation and cardiovascular hospitalisations in the United States: nationwide difference-in-differences analysis, 2012-2018

Population exposed to recreational cannabis legalisation by region, 2012–2018.

Study in peopleIndustry & policy

Saturday, October 24

Journal of AnesthesiaOct 24

The impact of dexmedetomidine on postoperative delirium and early postoperative cognitive impairment in elderly patients undergoing general surgery: a systematic review and meta-analysis

Meta-analysisPostoperative delirium

Friday, October 23

Kidney International ReportsOct 23

Opioids linked to higher death risk in chronic kidney disease

Estimated death risk over 28 days was 0.4% after one 90-day opioid prescription period versus 0.6% after six in adults with chronic kidney disease.Estimated death risk over 28 days was 0.4% after one 90-day opioid prescription period versus 0.6% after six in adults with chronic kidney disease.

Cohort · 21,440 peopleChronic kidney disease

Anesthesia and Pain MedicineOct 23

Inflammaging in older patients with cancer undergoing surgery: implications for anesthetic management

ReviewInflammation

Research SquareOct 23

Sedative reduced delirium after hip fracture surgery

In a preprint trial, delirium occurred in 21.2% of older patients given the sedative versus 45.7% given placebo within seven days of hip fracture surgery.In a preprint trial, delirium occurred in 21.2% of older patients given the sedative versus 45.7% given placebo within seven days of hip fracture surgery.

CONSORT flow diagram

Preprint: randomized trial · 490 peoplePostoperative delirium

Research SquareOct 23

Lung Cancer Incidence and Mortality in a Nationwide 45-year Prospective Cohort of Persons with Opioid Use Disorder

Kaplan–Meier survival curve from date of LC diagnosis to death due to LC (underlying or contributing cause) else censored alive.

Preprint: cohort study of 9,895 peopleLung cancer

Tuesday, October 20

Addiction & HealthOct 20

Opium Consumption and Myocardial Infarction in Osteoarthritis Patients: A Propensity Score Matched Cohort Study

Cohort study in peopleOsteoarthritis

Monday, October 19

Neurogastroenterology and MotilityOct 19

Gastrointestinal Symptom Events and Motility Alterations Associated With GLP-1 Receptor Agonists

Cohort study of 78,277 peoplePopulations

Friday, October 16

European Addiction ResearchOct 16

Higher death rates among opioid treatment recipients in Austria

Compared with Austria’s general population, age-adjusted death rates were 7.06 times as high for women and 3.86 times as high for men.Compared with Austria’s general population, age-adjusted death rates were 7.06 times as high for women and 3.86 times as high for men.

Age-specific mortality rates (a) and proportional mortality (b) among individuals in the OAT cohort and in the Austrian general population, by main causes of death (2002–2021).

Cohort · 26,031 peoplePopulations

Saturday, October 10

Disease-a-monthOct 10

Status Of GLP-1 drugs and their application in treating substance use disorders: A systematic review

Systematic review of studies in peopleInterventions

Friday, October 2

International Journal of Nursing Studies AdvancesOct 2

Background and design of the empowering cardiovascular health in grandfamilies (ECHG) study: A mixed methods study research protocol

Conceptual framework guiding the proposed study.

Study protocolCardiovascular disease

Tuesday, September 29

Osteoporosis InternationalSep 29

Impact of orthogeriatric care: prescription patterns in hospitalized older adults

Cohort study of 872 peopleInterventions

Monday, September 28

Archives of Physical Medicine and RehabilitationSep 28

Physical Performance and Central Nervous System-Active Analgesics Independently Predict 8-Year Fall Risk in Adults with or at Risk for Knee Osteoarthritis

Cohort study of 4,783 peopleKnee osteoarthritis

Thursday, September 24

bioRxivSep 24

Pupil size and pupil change correlate with distinct cortical neurochemical systems across the adult lifespan

Task-evoked pupillary and locus coeruleus responses by age group.

Preprint: cohort study of 89 peopleMechanisms

Wednesday, September 23

The Milbank QuarterlySep 23

US Life Expectancy and Increasing Mortality Rates: An Analysis of the Crisis

Computational studyPopulations

Friday, September 11

Journal of Addiction MedicineSep 11

The Overlapping Symptoms of Perimenopause and Opioid Withdrawal: When Hormone Therapy is "Even more Important for My Recovery than My Methadone"

Case reportHormone therapy

Thursday, September 10

Frontiers in PsychiatrySep 10

Non-randomized rapamycin augmentation of chronic self-administered ketamine provides subjective improvement in diverse phenotypes

Distribution of ketamine dose and correlation with opioid use.

Cohort study of 101 peopleRapamycin

Sunday, September 6

Frontiers in EndocrinologySep 6

Prehospital glucagon-like peptide-1 receptor agonists are not associated with reduced inpatient opioid exposure but with shorter hospital length of stay after total joint arthroplasty

Covariate balance before and after propensity-score matching.

Cohort study of 1,572 peoplePopulations

Friday, August 14

European Journal of Trauma and Emergency SurgeryAug 14

Effect of management in intermediate care unit versus conventional hospitalization on long-term mortality and autonomy in patients with rib fractures aged 75 years and older: a retrospective study

Cohort study of 196 peopleBones and joints

Thursday, August 13

Journal of Clinical MedicineAug 13

Glucagon-like Peptide-1 Receptor Agonists and Chronic Pain: Preclinical Antinociceptive Mechanisms, Indirect Metabolic-Functional Effects, and Clinical Considerations-A Narrative Review

Proposed preclinical spinal microglial mechanism of GLP-1 receptor-mediated suppression of nociceptive transmission.

ReviewGLP-1 receptor agonists

Wednesday, August 12

Research SquareAug 12

Development and Clinical Evaluation of the Unified Musculoskeletal Dysfunction Index and Unified Musculoskeletal Aging Index in Chronic Musculoskeletal Disorders

Preprint: randomized trial in 180 peopleMusculoskeletal disease

Drug and Alcohol DependenceAug 12

Substance use and epigenetic age acceleration: Associations with alcohol, tobacco, illicit drugs, and SUD severity

Cohort study of 2,276 peoplePopulations

Tuesday, August 11

Research SquareAug 11

Effectiveness of offering an integrated exercise intervention for psychological distress in patients receiving opioid agonist therapy: A randomised controlled trial

Preprint: randomized trial in 311 peopleExercise

Wednesday, August 5

BiogerontologyAug 5

Endurance training mitigates morphine-induced renal dysfunction in young and aged rats: involvement of oxidative stress, SIRT1, Klotho and TFAM

Experiments in ratsEndurance training

Tuesday, August 4

Brain, Behavior, and ImmunityAug 4

Disruption of hippocampal mitochondrial function underlies opioid-induced postoperative cognitive dysfunction in aged rats

Experiments in ratsOxidative phosphorylation

Wednesday, July 29

AgingJul 29

Transcriptomic aging clock analysis identifies key genes in opioid dependence

Computational studyBiomarkers

Thursday, June 25

Journal of XenobioticsJun 25

Chronic Opioid Use and Endocrine Disruption in Women: Mechanisms, Life-Course Vulnerabilities, and Reproductive Health Implications

ReviewReproductive system

Thursday, June 18

Archives of Gerontology and GeriatricsJun 18

Associations between fall risk increasing drugs (FRID) and fall & fall injuries in older Black and White men and women: the Health, Aging and Body Composition Study

Cohort study of 1,273 peoplePopulations

Saturday, June 13

Experimental GerontologyJun 13

Chronic co-prescription of opioids and benzodiazepines is associated with higher frailty prevalence in older US adults: A nationally representative cross-sectional analysis of NHANES 2005-2018

Cross-sectional study of 18,434 peoplePopulations

Wednesday, June 3

Bulletin of Experimental Biology and MedicineJun 3

Infarct-Limiting Efficacy of the μ₂‑Opioid Receptor Peptide Agonist Endomorphin‑1 in Metabolic Syndrome and Aging

Experiments in ratsMetabolic syndrome