AgingResearch.NewsJoin free

Opioid

Opioid has been studied in 6 papers since 2021: 1 trial and 4 observational studies in people. The newest story, Oct 16, 2026: “Higher death rates among opioid treatment recipients in Austria”.

Intervention

6 papers study it304 more mention it1 findingUpdated

PubChem

13 new papers in 30 daysSee all 310

“aMCI status was significantly associated with years since HIV diagnosis, time to care, and opioid exposure in age-adjusted models.”
Time since HIV diagnosis is linked to amnestic mild cognitive impairment (MCI) in older adults with HIVJournal of neurovirology2025doi:10.1007/s13365-025-01271-w

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

About aging: trials about aging, of every trial that tests the drug for any use.

  • 1 lab in 1 country
  • 3 trials, none about aging
  • Funders: National Institute on Drug Abuse and 6 more
  • Human trial1
  • Humans4
  • In silico1

What is Opioid linked with?

1

Studies link Opioid with 1 measure, most often amnestic mild cognitive impairment (1 study).

Amnestic mild cognitive impairment

upin humans1

1 study

  1. Opioid is associated with amnestic mild cognitive impairment in humans.

    “aMCI status was significantly associated with years since HIV diagnosis, time to care, and opioid exposure in age-adjusted models.”

    Humansin age-adjusted modelsn = 56

    Time since HIV diagnosis is linked to amnestic mild cognitive impairment (MCI) in older adults with HIV

    Journal of neurovirology

More on Amnestic mild cognitive impairment

Trial sponsors

Funding

12 grants since 2018

National Institute on Drug AbuseUS$10.7mNational Institute on AgingUS$839.5kNational Heart, Lung, and Blood InstituteUS$251.5k

Latest

Nov 2025: 8Dec 2025: 13Jan 2026: 4Feb 2026: 6Mar 2026: 7Apr 2026: 2May 2026: 1Jun 2026: 3Jul 2026: 3Aug 2026: 9Sep 2026: 6Oct 2026: 870 papers in 12 months
Kidney International Reports

Opioids linked to higher death risk in chronic kidney disease

Estimated death risk over 28 days was 0.4% after one 90-day opioid prescription period versus 0.6% after six in adults with chronic kidney disease.Estimated death risk over 28 days was 0.4% after one 90-day opioid prescription period versus 0.6% after six in adults with chronic kidney disease.

Cohort · 21,440 peopleChronic kidney disease
Paper
Research Square

Sedative reduced delirium after hip fracture surgery

In a preprint trial, delirium occurred in 21.2% of older patients given the sedative versus 45.7% given placebo within seven days of hip fracture surgery.In a preprint trial, delirium occurred in 21.2% of older patients given the sedative versus 45.7% given placebo within seven days of hip fracture surgery.

Preprint: randomized trial · 490 peoplePostoperative delirium
Paper
European Addiction Research

Higher death rates among opioid treatment recipients in Austria

Compared with Austria’s general population, age-adjusted death rates were 7.06 times as high for women and 3.86 times as high for men.Compared with Austria’s general population, age-adjusted death rates were 7.06 times as high for women and 3.86 times as high for men.

Cohort · 26,031 peoplePopulations
Paper

See all 310

Related