2 papers2 findings
Bone protection
upin mice1
Microbiota transplantation induces bone protection in mice.
“Transplantation of metformin-adapted microbiota reproduced the bone-protective and anti-inflammatory effects”
AnimalsOVX micemetformin-adapted microbiotabone
Gut microbe products helped metformin protect bone in mice
European journal of pharmacology14 Oct 2026
Ageing phenotypes
downin killifish1
Microbiota transplantation decreases ageing phenotypes in killifish.
“asah2 KO-derived microbiota transplantation attenuates ageing phenotypes”
Animalsasah2 KO-derived microbiota
Inhibition of the gut ceramidase Asah2 decelerates the vertebrate ageing rate
bioRxiv (Cold Spring Harbor Laboratory)4 May 2026Preprint
Experiments in mice with ovaries removed linked the drug’s bone benefits to short-chain fatty acids, small molecules made by gut bacteria.Experiments in mice with ovaries removed linked the drug’s bone benefits to short-chain fatty acids, small molecules made by gut bacteria.