Ls-d
Intervention1 paper2 findings
- Cells1
Outcomes
2Cell death
upin human cells1Very low certainty
1 study
Cell death
upin human cells1Very low certainty
Ls-d increases cell death in human cells.
Cellsin senescent lung cancer patient-derived organoids combined with lightlung cancer patient-derived organoid
Light- and enzyme-gated prodrugs target senescent cells · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 4 Oct 2026
Apoptosis
upin human cells1Very low certainty
1 study
Apoptosis
upin human cells1Very low certainty
Ls-d induces apoptosis in human cells.
Cellsin senescent cells following light activationsenescent cell
Light- and enzyme-gated prodrugs target senescent cells · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 4 Oct 2026
Latest
1Light- and enzyme-gated prodrugs target senescent cells
Pairing 390 nm irradiation with beta-galactosidase cleavage improved prodrug selectivity in senescence models and increased death in senescent lung…Pairing 390 nm irradiation with beta-galactosidase cleavage improved prodrug selectivity in senescence models and increased death in senescent lung cancer patient-derived organoids.