Ls-a
Intervention1 paper1 finding
- Cells1
Outcomes
1BRD4
downin human cells1Very low certainty
1 study
BRD4
downin human cells1Very low certainty
Ls-a decreases BRD4 in human cells.
Cellsin senescent cells following light activationsenescent cell
Light- and enzyme-gated prodrugs target senescent cells · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 4 Oct 2026
Latest
1Advanced ScienceCells
Light- and enzyme-gated prodrugs target senescent cells
Pairing 390 nm irradiation with beta-galactosidase cleavage improved prodrug selectivity in senescence models and increased death in senescent lung…Pairing 390 nm irradiation with beta-galactosidase cleavage improved prodrug selectivity in senescence models and increased death in senescent lung cancer patient-derived organoids.