Lactic acid bacteria

Intervention

6 papers8 findings

  • Animals1
  • Model organisms3

Outcomes

7

Lifespan

upin worms2

2 studies
  1. Lactic acid bacteria extends lifespan in worms.

    “Four beneficial strains showed significant lifespan extension”

    Model organismsisolated from food

    Feeding on lactic acid bacteria isolated from food extends the lifespan of Caenorhabditis elegans

    Letters in applied microbiologyFeb 23, 2024

  2. Lactic acid bacteria extends lifespan in worms.

    “The addition of lactic acid bacteria to OP50 led to a significant improvement in the median and overall survival in simulated biomes”

    Model organismsin simulated biomes (addition to OP50)

    Probiotic effects of Lactococcus lactis and Leuconostoc mesenteroides on stress and longevity in Caenorhabditis elegans

    Frontiers in physiologySep 12, 2023

Amyloid β expression

downin worms1

1 study
  1. Lactic acid bacteria decreases amyloid β expression in worms.

    “we review anti-aging and suppression of amyloid β expression in a C. elegans model fed lactic acid bacteria”

    Review

    Caenorhabditis elegans as a model host to study effects of lactic acid bacteria and functional food factors

    Bioscience, biotechnology, and biochemistryNov 23, 2024

More on Amyloid β expression

Spontaneous nematode mobility

upin worms1

1 study
  1. Lactic acid bacteria improves spontaneous nematode mobility in worms.

    “increased spontaneous nematode mobility, regardless of treatment with or without FUdR”

    Model organismsisolated from food

    Feeding on lactic acid bacteria isolated from food extends the lifespan of Caenorhabditis elegans

    Letters in applied microbiologyFeb 23, 2024

Cognitive function

upin reviews1

1 study
  1. Lactic acid bacteria improves cognitive function.

    “The potential anti-aging benefits postulated include restoring gut balance, enhancing antioxidant potential, and fortifying cognitive and mental faculties.”

    Review

    Lactic Acid Bacteria and Aging: Unraveling the Interplay for Healthy Longevity

    Aging and diseaseOct 10, 2023

Inflammation

downin reviews1

1 study
  1. Lactic acid bacteria inhibits inflammation.

    “They offer multifarious health benefits, including enhancing digestion, strengthening immune mechanisms, and mitigating inflammation.”

    Review

    Lactic Acid Bacteria and Aging: Unraveling the Interplay for Healthy Longevity

    Aging and diseaseOct 10, 2023

More on Inflammation

Metabolic disorders

downin rats1

1 study
  1. Lactic acid bacteria protects against metabolic disorders in rats.

    “selected LAB strains also enhanced lipid, renal, and liver profile of rats”

    Animalsin D-galactose-treated rats

    Lactobacillus Strains Alleviated Aging Symptoms and Aging-Induced Metabolic Disorders in Aged Rats

    Journal of medicinal foodDec 28, 2018

More on Metabolic disorders

Telomere length

downin rats1

1 study
  1. Lactic acid bacteria prevents telomere length in rats.

    “prevented the shortening of telomere length in D-gal-treated rats compared to the untreated control (P < .05)”

    Animalsin D-galactose-treated rats10 log CFU/rat/day12 weeks

    Lactobacillus Strains Alleviated Aging Symptoms and Aging-Induced Metabolic Disorders in Aged Rats

    Journal of medicinal foodDec 28, 2018

More on Telomere length

Funding

2 grants since 2020

Japan Society for the Promotion of ScienceJP¥22m

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