ISORHAMNETIN-3-O-GLUCOSIDE-7-O-RHAMNOSIDE

1. ISORHAMNETIN-3-O-GLUCOSIDE-7-O-RHAMNOSIDE activates autophagy in worms.

   “IGRh further stimulated the autophagy-lysosomal system and mitochondrial quality control”

   Model organisms

   Sea buckthorn flavonoid IGRh and its metabolites delay Caenorhabditis elegans aging via SIR-2.1/DAF-16-mediated IIS and autophagy-lysosomal pathways

   Phytomedicine : international journal of phytotherapy and phytopharmacology·14 Jul 2026

More on Autophagy

1. ISORHAMNETIN-3-O-GLUCOSIDE-7-O-RHAMNOSIDE improves motility in worms.

   “IGRh significantly extended lifespan and improved key aging-related phenotypes, including motility, intestinal barrier integrity, muscle structure, and lipid homeostasis, without impairing reproduction.”

   Model organisms

   Sea buckthorn flavonoid IGRh and its metabolites delay Caenorhabditis elegans aging via SIR-2.1/DAF-16-mediated IIS and autophagy-lysosomal pathways

   Phytomedicine : international journal of phytotherapy and phytopharmacology·14 Jul 2026

1. ISORHAMNETIN-3-O-GLUCOSIDE-7-O-RHAMNOSIDE extends lifespan in worms.

   “IGRh significantly extended lifespan”

   Model organisms

   Sea buckthorn flavonoid IGRh and its metabolites delay Caenorhabditis elegans aging via SIR-2.1/DAF-16-mediated IIS and autophagy-lysosomal pathways

   Phytomedicine : international journal of phytotherapy and phytopharmacology·14 Jul 2026