Lequesne Index

1. Glucosamine + chondroitin sulfate + curcumin decreases Lequesne Index in humans (F=7.091; P=0.009 at T2).

   “Lequesne Index showed reductions at T1 and T2 compared to T0 (F=9.535; P=0.0001), along with group effect, since the experimental group presented a lower score at T2 (F=7.091; P=0.009).”

   Human trialcombined with physical therapy in patients with knee osteoarthritis12 weeksn = 53

   The efficacy and safety of a combination of glucosamine hydrochloride, chondroitin sulfate and bio-curcumin with exercise in the treatment of knee osteoarthritis: a randomized, double-blind, placebo-controlled study

   European journal of physical and rehabilitation medicine·Mar 3, 2016

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1. Glucosamine decreases Lequesne Index in humans (from 9.4 +/- 1.8 to 3.4 +/- 1.9).

   “The Lequesne's score decreased to 3.4 +/- 1.9 (P < 0.05) and 3.4 +/- 1.8 (P < 0.05) after 4-week treatment comparing to 0-week in the GH (9.4 +/- 1.8) group”

   Human trialknee osteoarthritishydrochloride1440 mg/day4 weeksn = 71

   A multi-central, randomized, controlled clinical trial of glucosamine hydrochloride/sulfate in the treatment of knee osteoarthritis

   Zhonghua yi xue za zhi·Nov 16, 2005

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